Basic Information
VIS ID
TVIS30001427
Fusion event
HIV-LOC107984456 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.33
Reference genome
GRCh37/hg19
Start
132668537/132183992 (Hg38)
End
132669405/132183992 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
LOC107984456
Nearest miRNA
hsa-let-7i/Upstream/3889814; hsa-mir-6763/Downstream/398005;
Nearest TSS
ENST00000382841/Upstream/14169; ENST00000535242/Downstream/5703;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/4789, chr12-CpG: 129/Downstream/5153
Nearby gene
GALNT9(No orient, 12380)
Target sequence
GATGTGTCTTCTGCTCCTGGGAAGATAGAGCAGAGGTATTTTTCTCTATTCATCTCACTAAGCATGGCATAAAACTCTATATGAGAAAACTTAGGACCCTGCAGGGTGGAGAGAAGCAGGCTGGCTAGGGACCTCAGGACCCAAAGGATGATGTGGTGGTGAAGGCCTTGGATTTTCTTCTTGCTTCATCGATCCCATGCTTGGACTTGAAGAAGCTGGTAATCCAGAAACAAGGATCAAAAAATAAAAATTAAA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate