Basic Information
VIS ID
TVIS30001428
Fusion event
HIV-chrX integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
135720363/136638204 (Hg38)
End
135721033/136638204 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7f-2/Upstream/87244; hsa-mir-105-1/Downstream/2029507;
Nearest TSS
ENST00000429181/Upstream/87762; ENST00000370629/Downstream/9989;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/140264, chrX-CpG: 104/Downstream/128667
Nearby gene
LINC00892(No orient, 1339)
Target sequence
GTTGCCAGCAATCCTTGATGTTCTGCGGCTTGTAGACACATCTCTCCAATCCCTGCCTCTGTTTTTGCATGGCTGTTTTCCCTCTGTGTTTGTCTGTGTTCAAATTTCCCTCTTCTTATAAGATCACTAGTCATTGAATTAGGGCCCACCTTAATTCAGTTTGACCTTATATTAATTTCACTAATTACATTTACAAAGTATTTCCCCCCCAAAAAAGTCACATTCACAGGTGCCACATGGGCATGAATTTGGGGA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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