Basic Information
VIS ID
TVIS30001429
Fusion event
HIV-chr6 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
26037587/26037359 (Hg38)
End
26038207/26037359 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA6C
Nearest miRNA
hsa-mir-3691/Upstream/7465479; hsa-mir-10398/Downstream/1110267;
Nearest TSS
ENST00000381078/Upstream/3791; ENST00000612966/Downstream/6298;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/3800, chr6-CpG: 22/Downstream/6616
Nearby gene
HIST1H2AB(No orient, 3791)
Target sequence
GACTGATCCCTCCTACATCATACACATACACAGGCCACATTTGGAACATTGTTAGAGGTTCCTCTACCCAGTACAAATGTACTACAAATTATATATGTATTTTTAAATTTTTGAGTATCTTCAATAGTATATTTTCGTTAACTTTTGTAGTCAAAATGTCATTATAACATGTATTCAATATGCATAATTATTAGTCAGATGTTTTACATTCTTTCTTCATACTAAGTGATATGGTTTGGATATTTGTCCCCTCTA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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