Basic Information
VIS ID
TVIS30001430
Fusion event
HIV-chr15 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
91372372/90829142 (Hg38)
End
91372511/90829142 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10393/Upstream/822301; hsa-mir-1302-10/Downstream/2075257;
Nearest TSS
ENST00000557528/Upstream/20371; ENST00000559353/Downstream/39450;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/9714, chr15-CpG: 17/Downstream/41939
Nearby gene
BLM(No orient, 13680)
Nearest cancer related gene
BLM(TSG, No orient, 13680)
Target sequence
CCAAGGTCACCCAGCATGTCGGCAACAGGCAGGTTTGAAGAACTGGAAATGGTGACTCCAGACCTGGGGGCTGGGATTAGGGTGGCCCACTTCAGGGAGCAGGAAGGTCTTAAAAATTTAATTTTAATTTTTTTTTTTT
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
Curate