Basic Information
VIS ID
TVIS30001433
Fusion event
HIV-ZC3H18 integration
Validated
Yes
Detection method
QiaQuick PCR and Sequencing
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
25011556
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
88664521/88598113 (Hg38)
End
88665213/88598113 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZC3H18
miRNAs that regulate target gene
hsa-mir-1914-3p ; hsa-mir-29b-2-5p ; hsa-mir-93-3p ; hsa-mir-484 ; hsa-mir-18b-5p ; hsa-mir-106b-5p ; hsa-mir-218-5p ; hsa-mir-183-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-92a-3p ; hsa-mir-31-5p ; hsa-mir-18a-5p ; hsa-mir-17-5p ; hsa-let-7f-5p ; hsa-let-7a-5p
Nearest miRNA
hsa-mir-11401/Upstream/129082; hsa-mir-4722/Downstream/118165;
Nearest TSS
ENST00000527434/Upstream/11496; ENST00000568072/Downstream/1723;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/27188, chr16-CpG: 26/Downstream/24946
Target sequence
GGCTCTCTCTGGACCGAGGAAATCCCAGTTTTGTCAAGAACCACTCCTGTAATAGCATCTTTCTTGTCGGGATTTCTGCTGAATTGTGTTTACCTCCTTTGCATGCCGGAGTCCTCGTTCCCAGGCACTCTCTGTTGGGGGCTCTGGAGGGGGTGGAGGCAAAATTTCATCAACTACCGGCCCACCCTATTGAAAAACGAGAAGGGAGAAGGTGAGAAAGTAAAACTTTCAAGTGTACAGAGAAACCAGACAGTA
Reference
Wagner, T. A., et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science,2014, 345(6196): 570-573.
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