Basic Information
VIS ID
TVIS30001440
Fusion event
HIV-INTS11 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.33
Reference genome
GRCh37/hg19
Start
1253742/1318362 (Hg38)
End
1253742/1318362 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
INTS11
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-let-7b-5p ; hsa-mir-1226-3p ; hsa-mir-320a ; hsa-mir-23b-3p
Nearest miRNA
hsa-mir-12136/Upstream/5796; hsa-mir-101-1/Downstream/21288;
Nearest TSS
ENST00000473358/Upstream/912; ENST00000488011/Downstream/984;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/5249, chr1-CpG: 18/Downstream/580
Upstream sequence
aaatgcaggaagcccaacaaaaaggataaatatataaataaaactaagcaaatgttggtgttaccaggcattagaaatgatgtctttctgggtttaaaat
Downstream sequence
gtaCTGAGGGAGTTgccaggtgtggtgactcatgcctgtaatccgagcactttgagaggctgaggtgggaggatccctggagcccagcccaggagttcga
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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