Basic Information
VIS ID
TVIS30001462
Fusion event
HIV-MFN2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.22
Reference genome
GRCh37/hg19
Start
12053613/11993556 (Hg38)
End
12053613/11993556 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
MFN2
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-16-5p ; hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-99b-5p ; hsa-mir-221-3p ; hsa-mir-34a-5p ; hsa-mir-93-5p ; hsa-mir-92a-3p ; hsa-mir-1260b ; hsa-mir-3619-5p ; hsa-mir-195-3p ; hsa-mir-106b-5p ; hsa-mir-218-5p ; hsa-mir-4303 ; hsa-mir-6826-3p ; hsa-mir-3156-3p ; hsa-mir-610 ; hsa-mir-6751-3p ; hsa-mir-1199-5p ; hsa-mir-4653-5p ; hsa-mir-3921 ; hsa-mir-532-3p ; hsa-mir-2276-5p ; hsa-mir-6795-3p ; hsa-mir-6887-3p ; hsa-mir-4301 ; hsa-mir-483-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-106a-5p ; hsa-mir-17-5p ; hsa-mir-761
Nearest miRNA
hsa-mir-12136/Upstream/2026098; hsa-mir-101-1/Downstream/35602;
Nearest TSS
ENST00000473358/Upstream/11564; ENST00000492256/Downstream/25910;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/12820, chr1-CpG: 66/Downstream/25638
Upstream sequence
cgggcatggtggctcacacctgtaatcccagcactttgggaggccgaggcaggtggatcacgaggtcaggagatcgagaccatcctgtctaacacagtga
Downstream sequence
aaccccatctctactaaaaatacaaaaaattagccgggtgaggtggcgggcgcctgtagtcccagctacttgggaggctagggcaggagaatggtgtgaa
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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