Basic Information
VIS ID
TVIS30001464
Fusion event
HIV-DHRS3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.21
Reference genome
GRCh37/hg19
Start
12668809/12608804 (Hg38)
End
12668809/12608804 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
DHRS3
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-92a-3p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-130b-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-4719
Nearest miRNA
hsa-mir-12136/Upstream/29781; hsa-mir-101-1/Downstream/4250145;
Nearest TSS
ENST00000473358/Upstream/12496; ENST00000376221/Downstream/7892;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/12569, chr1-CpG: 124/Downstream/8174
Upstream sequence
AAGAGCAACCTGTTCCAAAGGGCaggaaggtgttcctcttgcagggcccaggtctgcattttcgagccctccccacgggcctagcatgggcctccagaac
Downstream sequence
catctagaacaggtcccatgcctctgtggtactggaatgcagctgataccctctcttgcctcttaagcagtcaactatactcccatggatttgccaccca
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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