Basic Information
VIS ID
TVIS30001490
Fusion event
HIV-MAN1C1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.11
Reference genome
GRCh37/hg19
Start
25960464/25633973 (Hg38)
End
25960464/25633973 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
MAN1C1
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-93-5p ; hsa-mir-20a-5p ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-3140-3p ; hsa-mir-3663-3p ; hsa-mir-552-3p ; hsa-mir-6885-3p ; hsa-mir-6769b-5p ; hsa-mir-6769a-5p ; hsa-mir-6871-5p ; hsa-mir-1273e ; hsa-mir-146a-5p ; hsa-mir-146b-5p ; hsa-mir-3689d ; hsa-mir-377-5p ; hsa-mir-455-3p ; hsa-mir-6086 ; hsa-mir-6134 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-665 ; hsa-mir-6807-5p ; hsa-mir-6840-3p ; hsa-mir-6851-5p ; hsa-mir-6880-5p ; hsa-mir-7153-5p ; hsa-mir-7847-3p
Nearest miRNA
hsa-mir-12136/Upstream/610387; hsa-mir-101-1/Downstream/272389;
Nearest TSS
ENST00000473358/Upstream/16123; ENST00000473891/Downstream/25138;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/15692, chr1-CpG: 16/Downstream/137440
Upstream sequence
ttttatgctttcaagaggttctgttttggtgcatatcaagctttggtttcaatatttagaactccttttagcatttcttgtagggctggtctggtagtga
Downstream sequence
caagttccttcaccatgtaaatgatattctttaaatatttgttttccaattgtttgttgccagtacatagaaatataatagggttttttctgtatattga
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate