Basic Information
VIS ID
TVIS30001509
Fusion event
HIV-EYA3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p35.3
Reference genome
GRCh37/hg19
Start
28355594/28029083 (Hg38)
End
28355594/28029083 (Hg38)
Orient
-
Location type
Intronic
Target gene
EYA3
miRNAs that regulate target gene
hsa-mir-30b-5p ; hsa-let-7c-5p ; hsa-mir-708-5p ; hsa-mir-2467-3p ; hsa-mir-1827 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-6856-5p ; hsa-mir-6758-5p
Nearest miRNA
hsa-mir-12136/Upstream/1474490; hsa-mir-101-1/Downstream/2710073;
Nearest TSS
ENST00000473358/Upstream/17997; ENST00000465645/Downstream/6596;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/68756, chr1-CpG: 23/Downstream/59504
Upstream sequence
tgttgggattacaggcatgagccactgcCAGCCAAGGACTGTGTTATACATAGTGTACATAATTTGCTTTTCCACATAATACCTCTAAGATTCATCTTTC
Downstream sequence
CAAGTCAGAACATATAAATCTATCTCATACTGACAAACATCATAGCTGTTCATTTTTATTTTCTTTTTATCATAATGCTCCTGAGTAACaatctttctaa
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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