Basic Information
VIS ID
TVIS30001564
Fusion event
HIV-STIL integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p33
Reference genome
GRCh37/hg19
Start
47729288/47263616 (Hg38)
End
47729288/47263616 (Hg38)
Orient
-
Location type
Intronic
Target gene
STIL
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-26b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-651-5p ; hsa-mir-7977 ; hsa-mir-4266 ; hsa-mir-3178 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4486 ; hsa-mir-5693 ; hsa-mir-383-3p ; hsa-mir-4779 ; hsa-mir-4695-5p
Nearest miRNA
hsa-mir-12136/Upstream/2718064; hsa-mir-101-1/Downstream/3796221;
Nearest TSS
ENST00000473358/Upstream/31396; ENST00000471289/Downstream/17441;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/31091, chr1-CpG: 51/Downstream/50419
Nearest cancer related gene
STIL(OG, No orient, 0)
Upstream sequence
aggcatcagagcaagaccctatttctataagaaacaaaaacgaaaaCACCTCGTTTTAACAGGCTGCATATAAACTAAACCATGGTACCTTTTAACTTGT
Downstream sequence
GTTACTTATATTTAAGACAACTTTCTTTGAAGCCTGGAAAACAAGCTGTTGATTTCTCCTGAACTTGATGGCAATGGAAATTTTTAGAGCATTTAAATAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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