Basic Information
VIS ID
TVIS30001626
Fusion event
HIV-HIST2H2BF integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
149779761/149808206 (Hg38)
End
149779761/149808206 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1F
Target gene
HIST2H2BF
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-26b-5p ; hsa-mir-1180-3p ; hsa-mir-760 ; hsa-mir-423-5p ; hsa-mir-296-3p ; hsa-mir-99b-3p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-125b-5p ; hsa-mir-25-3p ; hsa-let-7e-5p ; hsa-let-7a-5p
Nearest miRNA
hsa-mir-101-1/Upstream/1419843; hsa-mir-1182/Downstream/684139;
Nearest TSS
ENST00000473358/Upstream/15186; ENST00000578186/Downstream/3551;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/14773, chr1-CpG: 45/Downstream/3763
Upstream sequence
ATAACCTCTAATCACAGAATAAAAATGGAATGAGAATTCCATCTACCCAAATCAGACAATTAAAAAGTTGAAAGAGGTTACAGTAAAAACTGGGTAAAAC
Downstream sequence
TAAAACTTAAAAAATAATTTCAGAGGATACATGATATACTCGTCACACAGAAAACTCCAGTTGAACCTTATGGACTTGAGGAATGGATacctttgtgtct
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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