Basic Information
VIS ID
TVIS30001690
Fusion event
HIV-DENND1B integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
197673669/197704539 (Hg38)
End
197673669/197704539 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1K
Target gene
DENND1B
miRNAs that regulate target gene
hsa-mir-6869-5p ; hsa-mir-155-5p ; hsa-mir-4312 ; hsa-mir-532-5p ; hsa-mir-802 ; hsa-mir-365b-3p ; hsa-mir-365a-3p ; hsa-mir-195-3p
Nearest miRNA
hsa-mir-101-1/Upstream/1122058; hsa-mir-1182/Downstream/1154334;
Nearest TSS
ENST00000473358/Upstream/46189; ENST00000440885/Downstream/30990;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/502950, chr1-CpG: 103/Downstream/70262
Upstream sequence
ATCTCTCCCACTTGAAGGACCAACTCTTTAGCAAGGCAAACTGTGCCAAAACCTAGCTCATTTACTTTTATAGTTTTATCTCCCAATACTCTCCTGTACA
Downstream sequence
AAACCCTCCACTGTATCAAAAAAAGAAAAAATATATAATCAAAGCTCCTGAAATGCCATGTCAGTTGTCCCACTGGTTCCTCAATTGCCAAAAGAAGGAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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