Basic Information
VIS ID
TVIS30001726
Fusion event
HIV-CNST integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q44
Reference genome
GRCh37/hg19
Start
246737225/246573923 (Hg38)
End
246737225/246573923 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1I
Target gene
CNST
miRNAs that regulate target gene
hsa-mir-10a-5p ; hsa-mir-150-5p
Nearest miRNA
hsa-mir-101-1/Upstream/3227668; hsa-mir-3124/Downstream/628044;
Nearest TSS
ENST00000473358/Upstream/7409; ENST00000570141/Downstream/108185;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/6949, chr1-CpG: 42/Downstream/45972
Upstream sequence
GAGAGTTTCCATTTTCCTCCAGCTCTTCAGTGTAAGTGAAAAAATGTGCCCAGAATGTCTCTATAGATTATTCTGCCTTCCCTCACCTTTTAGTTTTTTC
Downstream sequence
CATGGAAAGCTGACAGGTCAGAATAGGCATATTTTATTAGAAACTCGAAGTGGTGGGGGGTAGAAGTACACATCTTTGCCTCTTTTTTCCTTCTTGATTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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