Basic Information
VIS ID
TVIS30001789
Fusion event
HIV-KIF11 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q23.33
Reference genome
GRCh37/hg19
Start
94397324/92637567 (Hg38)
End
94397324/92637567 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
KIF11
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-340-5p ; hsa-mir-186-5p ; hsa-mir-34a-5p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-4495 ; hsa-mir-6507-5p ; hsa-mir-6516-3p ; hsa-mir-96-3p
Nearest miRNA
hsa-mir-107/Upstream/3044740; hsa-mir-1287/Downstream/3426748;
Nearest TSS
ENST00000439456/Upstream/44281; ENST00000551454/Downstream/52384;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/44165, chr10-CpG: 184/Downstream/51369
Upstream sequence
TGTTCCTTGGTTGAGTCACAAAAGCAATGTGGAAACCTAACTGAAGACCTGAAGACAATAAAGCAGACCCATTCCCAGGTATGTTGTTTAGCGGACTTGG
Downstream sequence
GGAGTACAGAAAGAGAGTTTTAGGATGATTTGATATGACTTGATAATTAATCTATGTTACACAATCTGAATACTGTAAAAGCTGAAACCTGAAAATACCA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate