Basic Information
VIS ID
TVIS30001793
Fusion event
HIV-WBP1L integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q24.32
Reference genome
GRCh37/hg19
Start
104518249/102758492 (Hg38)
End
104518249/102758492 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
WBP1L
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-155-5p ; hsa-mir-19b-3p ; hsa-mir-760 ; hsa-mir-615-3p ; hsa-mir-320a ; hsa-mir-2110 ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-6733-5p ; hsa-mir-6739-5p ; hsa-mir-3153 ; hsa-mir-8089 ; hsa-mir-4700-5p ; hsa-mir-4667-5p ; hsa-mir-582-3p
Nearest miRNA
hsa-mir-107/Upstream/321908; hsa-mir-1307/Downstream/635761;
Nearest TSS
ENST00000439456/Upstream/14522; ENST00000369889/Downstream/17757;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/43538, chr10-CpG: 28/Downstream/95751
Upstream sequence
ctggcaaccactcatctacttcctgtttttatggatttatctattctggacatttcatatgaatggaaccatacaccatgtggtcttttatgactggttt
Downstream sequence
tctttacttagcatgttttcaaggttcatccatgttgtagcatgtatcaatacttcatacctttttatggtcaattaatgtaggtccagccctatggggc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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