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TVIS30001815
Basic Information
VIS ID
TVIS30001815
Fusion event
HIV-PLEKHA1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q26.13
Reference genome
GRCh37/hg19
Start
124172776/122413260 (Hg38)
End
124172776/122413260 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
;
FRA10F
;
FRA10A
;
FRA10B
Target gene
PLEKHA1
miRNAs that regulate target gene
hsa-mir-590-3p
;
hsa-mir-335-5p
;
hsa-mir-124-3p
;
hsa-mir-93-5p
;
hsa-mir-32-5p
;
hsa-mir-26b-5p
;
hsa-mir-21-5p
;
hsa-mir-769-5p
;
hsa-mir-25-3p
;
hsa-mir-92a-3p
;
hsa-mir-125b-2-3p
;
hsa-mir-190a-3p
;
hsa-mir-363-3p
;
hsa-mir-367-3p
;
hsa-mir-338-3p
;
hsa-mir-92b-3p
;
hsa-mir-634
;
hsa-mir-1179
;
hsa-mir-4310
;
hsa-mir-5011-5p
;
hsa-mir-5697
;
hsa-mir-7157-5p
;
hsa-mir-371a-5p
;
hsa-mir-372-5p
;
hsa-mir-373-5p
;
hsa-mir-616-5p
;
hsa-mir-630
;
hsa-mir-371b-5p
;
hsa-mir-6883-3p
;
hsa-mir-15a-5p
;
hsa-mir-16-5p
;
hsa-mir-103a-3p
;
hsa-mir-107
;
hsa-mir-15b-5p
;
hsa-mir-195-5p
;
hsa-mir-424-5p
;
hsa-mir-497-5p
;
hsa-mir-3607-5p
;
hsa-mir-4524a-5p
;
hsa-mir-5197-5p
;
hsa-mir-4524b-5p
;
hsa-mir-6838-5p
;
hsa-let-7e-3p
;
hsa-mir-545-3p
;
hsa-mir-570-5p
;
hsa-mir-3148
;
hsa-mir-548ag
;
hsa-mir-548ai
;
hsa-mir-4477a
;
hsa-mir-4678
;
hsa-mir-548ba
;
hsa-mir-3973
;
hsa-mir-124-5p
;
hsa-mir-3607-3p
;
hsa-mir-1206
;
hsa-mir-3650
;
hsa-mir-7154-5p
;
hsa-mir-411-5p
;
hsa-mir-520h
;
hsa-mir-520g-3p
;
hsa-mir-4272
;
hsa-mir-4470
;
hsa-mir-548o-3p
;
hsa-mir-1323
;
hsa-mir-1278
;
hsa-mir-646
;
hsa-mir-503-5p
;
hsa-mir-1183
;
hsa-mir-101-3p
;
hsa-mir-433-3p
;
hsa-mir-6853-3p
;
hsa-mir-4455
;
hsa-mir-8060
;
hsa-mir-514b-5p
;
hsa-mir-513c-5p
;
hsa-mir-454-5p
;
hsa-mir-6866-3p
;
hsa-mir-188-5p
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-450a-1-3p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-7977
;
hsa-mir-4483
;
hsa-mir-1293
;
hsa-mir-6766-5p
;
hsa-mir-6756-5p
;
hsa-mir-6745
;
hsa-mir-363-5p
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-1273f
;
hsa-mir-4708-5p
;
hsa-mir-6088
;
hsa-mir-4770
;
hsa-mir-143-3p
;
hsa-mir-383-3p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
Nearest miRNA
hsa-mir-107/Upstream/2454668; hsa-mir-202/Downstream/3705;
Nearest TSS
ENST00000439456/Upstream/1489;
ENST00000528446/Downstream/41393;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/37843
,
chr10-CpG: 225/Downstream/47562
Upstream sequence
aaatatttttgtttatttcaaaagtatttattataaaaaatttGGAAATTACATAACATTTAAAACTTCTCATGATTTCTCTGAGCCTTTCTTCATGTAC
Downstream sequence
TTTTCACCTCAGAAATGGAGATATGAGTtgtatattacattttgtaaacagattttttcacttgtatcatgaacattttccaagtcatcagaaatccttt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Active CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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