Basic Information
VIS ID
TVIS30001818
Fusion event
HIV-EEF1AKMT2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q26.13
Reference genome
GRCh37/hg19
Start
126454666/124766097 (Hg38)
End
126454666/124766097 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10F ; FRA10A ; FRA10B
Target gene
EEF1AKMT2
miRNAs that regulate target gene
hsa-mir-484 ; hsa-mir-4668-5p ; hsa-mir-450b-5p ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-548aw ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-3121-5p ; hsa-mir-6782-3p
Nearest miRNA
hsa-mir-107/Upstream/2349030; hsa-mir-202/Downstream/266686;
Nearest TSS
ENST00000439456/Upstream/306; ENST00000298492/Downstream/8800;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/21646, chr10-CpG: 71/Downstream/25426
Upstream sequence
GAAATAAGAtttcttgaagacaggagtcttgctatgttgcccgggatagacttgaaaacctgagctaagcaatcctcccatctcagccttcctaagtaga
Downstream sequence
tgtggccacagCACTCAGCTATGGGAATAAGATTTTTAACTTATATTCCTAGTGTGTAACCTAAAATAAACACGGTAGATCAAAAGTTCTTGGGCCTTgg
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate