Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene6490894564851642648882966482338764844569648467496486735764841546648458446483672764837565648352996483570164866166
Basic Information
VIS ID
TVIS30001875
Fusion event
HIV-EHD1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
64633638/64866166 (Hg38)
End
64633638/64866166 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
EHD1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-34a-5p ; hsa-mir-7-5p ; hsa-mir-6739-5p ; hsa-mir-670-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-4329 ; hsa-mir-6859-3p ; hsa-mir-7113-3p ; hsa-mir-4324 ; hsa-mir-4319 ; hsa-mir-125b-5p ; hsa-mir-4732-3p ; hsa-mir-125a-5p ; hsa-mir-345-3p ; hsa-mir-645 ; hsa-mir-1226-3p ; hsa-mir-26b-5p ; hsa-mir-19b-3p ; hsa-mir-26a-5p ; hsa-mir-19a-3p
Nearest miRNA
hsa-mir-1237/Upstream/497463; hsa-let-7a-2/Downstream/12357;
Nearest TSS
ENST00000527297/Upstream/6121; ENST00000413292/Downstream/9500;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/11392, chr11-CpG: 124/Downstream/11791
Upstream sequence
ttgcagcactattcacgatagcaaagatggaatccacctaaatacccatcaacagtagactggataaagaaaacatggtacatataccacagagaatact
Downstream sequence
atccacccataaaaaggaacaagatcatgacctttgcagcaacatggatggagctggagaccattatcctcagcaaactaacactagaatagaaaaccaa
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate