Basic Information
VIS ID
TVIS30001946
Fusion event
HIV-DYNC2H1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
103112175/103241446 (Hg38)
End
103112175/103241446 (Hg38)
Orient
+
Location type
Intronic
Target gene
DYNC2H1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-124-3p ; hsa-mir-331-3p ; hsa-mir-125b-5p ; hsa-let-7a-5p
Nearest miRNA
hsa-mir-10392/Upstream/1721541; hsa-let-7a-2/Downstream/608460;
Nearest TSS
ENST00000527297/Upstream/36535; ENST00000525306/Downstream/40711;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/149126, chr11-CpG: 43/Downstream/795231
Upstream sequence
TATATTTAATCATGGAATACAGAGATAAAATGTACCATAGAAATCTTATCTAAATCTGTCTGGAGACGTAAAATAAGATGACAACAAACTTTTAAGTACC
Downstream sequence
CTTTGAAAAACTTAAGCATGTTTTCTTTGCTAAAAACATTTTGAAATGTTACCTTTCTTCTTTTCATTTAACTGCATCAGATCATTGGTTTGAAATCATG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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