Basic Information
VIS ID
TVIS30001960
Fusion event
HIV-IL10RA integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
117871165/118000450 (Hg38)
End
117871165/118000450 (Hg38)
Orient
-
Location type
UTR3
Fragile sites / regions
FRA11B
Target gene
IL10RA
miRNAs that regulate target gene
hsa-mir-8064 ; hsa-mir-483-3p ; hsa-mir-138-5p ; hsa-mir-6089 ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-548q ; hsa-mir-556-5p ; hsa-mir-15a-5p ; hsa-mir-185-5p ; hsa-mir-211-5p
Nearest miRNA
hsa-mir-10392/Upstream/4550362; hsa-let-7a-2/Downstream/643550;
Nearest TSS
ENST00000527297/Upstream/5491; ENST00000519126/Downstream/76562;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/13867, chr11-CpG: 77/Downstream/145072
Upstream sequence
TATCTCCCTCTCTCCAACAAATGGAGTAGCATCCCCCTGGGGCACTTGCTGAGGCCAAGCCACTCACATCCTCACTTTGCTGCCCCACCATCTTGCTGAC
Downstream sequence
AACTTCCAGAGAAGCCATGGTTTTTTGTATTGGTCATAACTCAGCCCTTTGGGCGGCCTCTGGGCTTGGGCACCAGCTCATGCCAGCCCCAGAGGGTCAG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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