Basic Information
VIS ID
TVIS30002026
Fusion event
HIV-ITPR2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p11.23
Reference genome
GRCh37/hg19
Start
26812106/26659173 (Hg38)
End
26812106/26659173 (Hg38)
Orient
+
Location type
Exonic
Target gene
ITPR2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-935 ; hsa-mir-877-3p ; hsa-mir-324-5p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-187-3p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6752-3p ; hsa-mir-4793-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/785094; hsa-let-7i/Downstream/15664527;
Nearest TSS
ENST00000382841/Upstream/28459; ENST00000544111/Downstream/56555;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/462976, chr12-CpG: 101/Downstream/173376
Upstream sequence
TCTCCACTAGAAAAGAATACCGCATGAATCATTTCAAACCTTGGCTCCCGATTTCTCCTGAGTAAACTGACAAATGTTTCTATTTCTTTTGCTGTGATAT
Downstream sequence
GTTTCTCTAGTAGTTTTCTGTTGTTGTGCAACAAAGCTGTGATAGTATCTTCTGCCAAAATATCATAGCCAATCTGGGACTGCATGACACAGAAATTCTT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate