Basic Information
VIS ID
TVIS30002027
Fusion event
HIV-FGFR1OP2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p11.23
Reference genome
GRCh37/hg19
Start
27113758/26960825 (Hg38)
End
27113758/26960825 (Hg38)
Orient
-
Location type
Intronic
Target gene
FGFR1OP2
miRNAs that regulate target gene
hsa-mir-361-5p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-3187-3p ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-1200 ; hsa-mir-378a-5p ; hsa-mir-6131 ; hsa-mir-3663-5p ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-4716-5p ; hsa-mir-4781-3p ; hsa-mir-3156-3p ; hsa-mir-4284 ; hsa-mir-4772-3p ; hsa-mir-4638-5p ; hsa-mir-532-3p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-4301 ; hsa-mir-6890-3p ; hsa-mir-711 ; hsa-mir-6859-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p
Nearest miRNA
hsa-mir-1244-3/Upstream/1086746; hsa-let-7i/Downstream/15362875;
Nearest TSS
ENST00000382841/Upstream/22325; ENST00000538172/Downstream/171;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/21901, chr12-CpG: 64/Downstream/53238
Upstream sequence
CAAATAAATGAAATTTATTAAAAGAATGTTGTGTCTTTAATAGCCATGCTGTTCAGTGTAGAAACTTTAAATCTCTCATTAATTTTCTGTGTATTGTATC
Downstream sequence
ATGTACAGCCTGTTAGATATTTGCAGGTTTTATAGGTTATTCAGTCCAACGCTTTATTTATTTGCTCTTGTTAGTTGTTGCTGTGAAACAGTCATTTCCT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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