Basic Information
VIS ID
TVIS30002087
Fusion event
HIV-GIT2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.11
Reference genome
GRCh37/hg19
Start
110372192/109934387 (Hg38)
End
110372192/109934387 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
GIT2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-26a-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-218-5p ; hsa-mir-210-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p
Nearest miRNA
hsa-let-7i/Upstream/100951; hsa-mir-1178/Downstream/1369755;
Nearest TSS
ENST00000382841/Upstream/1343; ENST00000612793/Downstream/4590;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/33601, chr12-CpG: 45/Downstream/61587
Upstream sequence
AGTCTCCAGGTATGAAATATGGCAACATACACTCTTGGTCAGGTGAGGCCACACAACAGTACAGAAACATAATTCACCCCTCCTCACGTCAGTCATTTAC
Downstream sequence
TTCTCATGTGTTTCATCGTCCCAATTTCTAGAAAGAGAAAGGATTTCCATGCAAAAGGCCACAGAAGTGAAAAATAAAGGACTGAAAAAATTCCTTAAAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate