Basic Information
VIS ID
TVIS30002101
Fusion event
HIV-OAS3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.13
Reference genome
GRCh37/hg19
Start
113380003/112942198 (Hg38)
End
113380003/112942198 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12E ; FRA12D
Target gene
OAS3
miRNAs that regulate target gene
hsa-mir-502-5p ; hsa-mir-1273f ; hsa-mir-4708-5p ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-143-3p
Nearest miRNA
hsa-let-7i/Upstream/247022; hsa-mir-1178/Downstream/216915;
Nearest TSS
ENST00000382841/Upstream/3652; ENST00000546800/Downstream/8375;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/3510, chr12-CpG: 115/Downstream/114386
Upstream sequence
TTTCCCTCAGCCACTGCCTGGAGCGGTTACTGCTCAGCCCTTCCACAAATACTCCCGAAAGCTAAGCCAAGTGGACATGTGGCTAGCAGTAGGGGCCTGG
Downstream sequence
GGACGAAACCAGAATTCTGCAAAATCTTGTATTTTATGTTGAAAACATCAATGTGATTTTTGTGTTCTCCTTCGTAATACACGTATGCTTGAGTTAAGAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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