Basic Information
VIS ID
TVIS30002102
Fusion event
HIV-OAS2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.13
Reference genome
GRCh37/hg19
Start
113423903/112986098 (Hg38)
End
113423903/112986098 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12E ; FRA12D
Target gene
OAS2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-132-3p ; hsa-mir-7-5p ; hsa-mir-620 ; hsa-mir-4531 ; hsa-mir-1270 ; hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-5192 ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-6823-3p ; hsa-mir-2114-3p ; hsa-mir-4635 ; hsa-mir-4670-3p ; hsa-mir-6751-3p ; hsa-mir-1199-5p ; hsa-mir-148a-5p
Nearest miRNA
hsa-let-7i/Upstream/290922; hsa-mir-1178/Downstream/173015;
Nearest TSS
ENST00000382841/Upstream/7496; ENST00000548941/Downstream/12147;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/47410, chr12-CpG: 115/Downstream/70486
Upstream sequence
aaagatgttttcctgtagatgtgtctatagtgttggttgagtggagcgctttggctttgattctgtgtgggcacagttagtggagcctccacatgatttc
Downstream sequence
attagcatcagtgttgtctgtgagctcctcagtggctgacagtgtagttgttaatggagtctgtggaaaggctgtgctgggaacagggacatcaggcagg
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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