Basic Information
VIS ID
TVIS30002118
Fusion event
HIV-P2RX7 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.31
Reference genome
GRCh37/hg19
Start
121614639/121176836 (Hg38)
End
121614639/121176836 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
P2RX7
miRNAs that regulate target gene
hsa-mir-186-5p ; hsa-mir-150-5p ; hsa-mir-218-1-3p ; hsa-mir-1200 ; hsa-mir-378a-5p ; hsa-mir-9-3p ; hsa-mir-4682 ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-876-5p ; hsa-mir-3167 ; hsa-mir-6880-3p ; hsa-mir-4312 ; hsa-mir-1324 ; hsa-mir-4524b-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-3191-5p ; hsa-mir-627-3p ; hsa-mir-130b-5p ; hsa-mir-3921 ; hsa-mir-4653-5p ; hsa-mir-301b-5p ; hsa-mir-301a-5p ; hsa-mir-146a-3p ; hsa-mir-216b-5p ; hsa-mir-640 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-186-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-6778-3p ; hsa-mir-3653-5p ; hsa-mir-520h ; hsa-mir-520g-3p
Nearest miRNA
hsa-let-7i/Upstream/453570; hsa-mir-3612/Downstream/267437;
Nearest TSS
ENST00000382841/Upstream/43865; ENST00000619282/Downstream/14032;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/80716, chr12-CpG: 75/Downstream/33066
Upstream sequence
gcgagactctgtctcaaaaaaaaaaaaaaaaaaaaaCCCACGAGGCCACCCAGACATTCCTTCCCTCTGCTTCTGAAGTAATGTCAAACCTTTTGGAGGA
Downstream sequence
GAAGCTTGTCTGAAACCCTCACCTTGTATGGAGAAATGATAGCCCTTCAGTGGGTCTCCCCTTAATGTGTGGGCCCCAGTGCTTGCTCATGTAAAACCTT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate