Basic Information
VIS ID
TVIS30002160
Fusion event
HIV-DLEU1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
50665106/50090970 (Hg38)
End
50665106/50090970 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
DLEU1
miRNAs that regulate target gene
hsa-mir-640 ; hsa-mir-4264 ; hsa-mir-4797-3p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-622 ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-378a-5p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3653-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-4713-5p ; hsa-mir-506-3p ; hsa-mir-124-3p ; hsa-mir-2116-3p ; hsa-mir-4736 ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-488-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-3910 ; hsa-mir-3714
Nearest miRNA
hsa-mir-15a/Upstream/41769; hsa-mir-1267/Downstream/1257597;
Nearest TSS
ENST00000623511/Upstream/8978; ENST00000413510/Downstream/34571;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/8698, chr13-CpG: 368/Downstream/32878
Nearest cancer related gene
DLEU1(TSG, No orient, 0)
Upstream sequence
TTGTCTTTTATGTATATTAGCATGATTGAACTTCATCCATTTAGCCTTATTGAATACTGTACTTTGTTTCTCTTCAGGAAAATTACAGTTTGATATCTTG
Downstream sequence
TGGGACAGAAGGTTTCATCTTTCAGTCATCAGAGAGCAAAGTAGGAAAGACTTAGAGAGGCAAAGTCCCTCTGCACCTAAGGATACACTATTTTTACTCT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate