Basic Information
VIS ID
TVIS30002231
Fusion event
HIV-MPP5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
67737415/67270698 (Hg38)
End
67737415/67270698 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA14B
Target gene
MPP5
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-130b-3p ; hsa-mir-155-5p ; hsa-mir-7-5p ; hsa-mir-148a-3p ; hsa-mir-192-5p ; hsa-mir-21-5p ; hsa-mir-93-3p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-520e ; hsa-mir-519c-3p ; hsa-mir-520a-3p ; hsa-mir-519b-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-520d-3p ; hsa-mir-519a-3p ; hsa-mir-548a-3p ; hsa-mir-548e-3p ; hsa-mir-548f-3p ; hsa-mir-302e ; hsa-mir-4639-5p ; hsa-mir-548ar-3p ; hsa-mir-548az-3p ; hsa-mir-6074 ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-6817-5p ; hsa-mir-4769-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-5683 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181a-5p ; hsa-mir-181b-5p
Nearest miRNA
hsa-mir-208a/Upstream/1799512; hsa-mir-1185-1/Downstream/171157;
Nearest TSS
ENST00000550708/Upstream/29071; ENST00000556724/Downstream/67078;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/28768, chr14-CpG: 97/Downstream/88724
Upstream sequence
TTTTTAAAGAGAGGGAGAGTGCAATTGCTTTGGACTGGGAGGACTTTTTCACTTTTATGATGTATATAGACTACATGTATGGGCTAGAGTATTTGTGGAG
Downstream sequence
TGCCTGCTTAAAAATTATAATcttaatgctaaaactataggatacagtataatgtttctttaattctggaagaactttaggatctttcattgcctTCATT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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