Basic Information
VIS ID
TVIS30002233
Fusion event
HIV-RAD51B integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
68636777/68170060 (Hg38)
End
68636777/68170060 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA14C
Target gene
RAD51B
miRNAs that regulate target gene
hsa-mir-484 ; hsa-mir-4668-5p ; hsa-mir-2053 ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-30b-3p ; hsa-mir-3689a-3p ; hsa-mir-1273h-5p ; hsa-mir-569 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-766-5p ; hsa-mir-6871-5p ; hsa-mir-4496 ; hsa-mir-4506
Nearest miRNA
hsa-mir-208a/Upstream/728130; hsa-mir-1185-1/Downstream/4346760;
Nearest TSS
ENST00000550708/Upstream/39864; ENST00000554575/Downstream/217077;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/494895, chr14-CpG: 40/Downstream/458238
Upstream sequence
TATGGACTCTTAGCTGTGGTGGAAAGAACCATTGAAACTCTCTCAGCCTTTAGTTCTTCATTAGGAAGATGCCTTTCTTACTGAGGGTTGTAATGATTGT
Downstream sequence
GAAGTCCAGTTTTCTGACTTCTCCATTAGGGAATAAGAGAACTCTTTGGTTTTAAATTGAAAGATGGAGTGATTCACTCTCCAGTGTAGGAGGGAACCTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate