Basic Information
VIS ID
TVIS30002236
Fusion event
HIV-DCAF5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
69606794/69140077 (Hg38)
End
69606794/69140077 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA14C
Target gene
DCAF5
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-218-5p ; hsa-mir-653-5p ; hsa-mir-1261 ; hsa-mir-7515 ; hsa-mir-5191 ; hsa-mir-4781-3p ; hsa-mir-3154 ; hsa-mir-409-3p ; hsa-mir-4446-5p ; hsa-mir-3679-3p ; hsa-mir-6826-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-6839-3p ; hsa-mir-4507 ; hsa-mir-3940-5p
Nearest miRNA
hsa-mir-208a/Upstream/1698147; hsa-mir-1185-1/Downstream/3376743;
Nearest TSS
ENST00000550708/Upstream/21883; ENST00000622466/Downstream/12522;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/159968, chr14-CpG: 163/Downstream/11542
Upstream sequence
AAGACAGAGAggccaggcgcagtggctcacacttataatcctagcacattgggaggacgagggggattgcctgagctcaggagatcgagactagcctggg
Downstream sequence
cgacgtagagaaatctcgtctctactaaaactacaaaaaattagctgggcatggtggtgcacacctataatctcagctacttgggaagctgaggcacgag
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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