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Viral Integration Site DataBase
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TVIS30002340
Basic Information
VIS ID
TVIS30002340
Fusion event
HIV-MAP2K1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q22.31
Reference genome
GRCh37/hg19
Start
66683830/66391492 (Hg38)
End
66683830/66391492 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA15A
Target gene
MAP2K1
miRNAs that regulate target gene
hsa-mir-424-5p
;
hsa-mir-34a-5p
;
hsa-mir-1826
;
hsa-mir-497-5p
;
hsa-mir-128-3p
;
hsa-mir-181a-5p
;
hsa-mir-101-3p
;
hsa-mir-93-3p
;
hsa-mir-30c-5p
;
hsa-mir-142-5p
;
hsa-mir-559
;
hsa-mir-548b-5p
;
hsa-mir-548a-5p
;
hsa-mir-548c-5p
;
hsa-mir-548d-5p
;
hsa-mir-548j-5p
;
hsa-mir-548k
;
hsa-mir-548l
;
hsa-mir-548h-5p
;
hsa-mir-548i
;
hsa-mir-548w
;
hsa-mir-548y
;
hsa-mir-548o-5p
;
hsa-mir-548ab
;
hsa-mir-548ad-5p
;
hsa-mir-548ae-5p
;
hsa-mir-548ak
;
hsa-mir-548am-5p
;
hsa-mir-451b
;
hsa-mir-548ap-5p
;
hsa-mir-548aq-5p
;
hsa-mir-548ar-5p
;
hsa-mir-548as-5p
;
hsa-mir-548au-5p
;
hsa-mir-5590-3p
;
hsa-mir-548av-5p
;
hsa-mir-548ay-5p
;
hsa-mir-6507-5p
;
hsa-mir-8054
;
hsa-mir-548bb-5p
;
hsa-mir-624-5p
;
hsa-mir-181b-5p
;
hsa-mir-494-3p
;
hsa-mir-34c-5p
;
hsa-mir-34b-3p
;
hsa-mir-449a
;
hsa-mir-448
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-889-3p
;
hsa-mir-6856-5p
;
hsa-mir-6758-5p
Nearest miRNA
hsa-mir-10393/Upstream/351160; hsa-mir-11181/Downstream/105466;
Nearest TSS
ENST00000557528/Upstream/4655;
ENST00000566326/Downstream/61962;
Nearest CpG islands
None/Target,
chr15-CpG: 55/Upstream/3867
,
chr15-CpG: 32/Downstream/106103
Upstream sequence
attctcctgcctcagcctcccaagtagctgggactacaggcgcccaccactgcgtccagctaattttttgtatttttagtagagatggggtttcaccatg
Downstream sequence
ttagccaggatggtctcgatctcctgatctcgtgatcccaaagtgctgggattacaggcgtgagccactgtgcccagccTGCACTGCCTTTTTTTGACtc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Active CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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