Basic Information
VIS ID
TVIS30002343
Fusion event
HIV-PIAS1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q23
Reference genome
GRCh37/hg19
Start
68375164/68082826 (Hg38)
End
68375164/68082826 (Hg38)
Orient
+
Location type
Intronic
Target gene
PIAS1
miRNAs that regulate target gene
hsa-mir-424-5p ; hsa-mir-124-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-5011-5p ; hsa-mir-3171 ; hsa-mir-5683 ; hsa-mir-101-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-5580-3p ; hsa-mir-4789-3p ; hsa-let-7g-3p ; hsa-let-7a-2-3p ; hsa-mir-1278 ; hsa-mir-1183 ; hsa-mir-340-5p
Nearest miRNA
hsa-mir-10393/Upstream/1585792; hsa-mir-11181/Downstream/719024;
Nearest TSS
ENST00000557528/Upstream/28250; ENST00000564009/Downstream/63836;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/27756, chr15-CpG: 64/Downstream/146254
Nearest cancer related gene
PIAS1(TSG, No orient, 0)
Upstream sequence
tagagtcctcaaagaaaaaattaaacagctgcatagacctactacatagaatatagagaaaaaaatgccagaagaactagctaaaaagacttgaaagtgg
Downstream sequence
ttgcctcggggatttgaaaattgtggggtatgttaaagggggaagggactgctgtttttcttgtaaaactttttggttttttaaattgtgttcacgtCTG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate