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Viral Integration Site DataBase
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TVIS30002346
Basic Information
VIS ID
TVIS30002346
Fusion event
HIV-TLE3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q23
Reference genome
GRCh37/hg19
Start
70378754/70086415 (Hg38)
End
70378754/70086415 (Hg38)
Orient
-
Location type
Intronic
Target gene
TLE3
miRNAs that regulate target gene
hsa-mir-10a-5p
;
hsa-mir-296-3p
;
hsa-mir-615-3p
;
hsa-mir-505-3p
;
hsa-mir-196b-5p
;
hsa-mir-222-3p
;
hsa-mir-34a-5p
;
hsa-mir-93-5p
;
hsa-mir-92a-3p
;
hsa-mir-18a-5p
;
hsa-mir-1260b
;
hsa-mir-6858-5p
;
hsa-mir-8085
;
hsa-mir-4689
;
hsa-mir-6731-5p
;
hsa-mir-765
;
hsa-mir-4644
;
hsa-mir-4306
;
hsa-mir-185-5p
;
hsa-mir-7160-5p
;
hsa-mir-6133
;
hsa-mir-6129
;
hsa-mir-6130
;
hsa-mir-6127
;
hsa-mir-4510
;
hsa-mir-4419a
;
hsa-mir-4784
;
hsa-mir-3150b-3p
;
hsa-mir-6760-5p
;
hsa-mir-4786-5p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-6873-5p
;
hsa-mir-6758-5p
;
hsa-mir-6856-5p
;
hsa-mir-6739-5p
;
hsa-mir-767-5p
;
hsa-mir-648
;
hsa-mir-1911-3p
;
hsa-mir-595
;
hsa-mir-5583-5p
;
hsa-mir-4311
;
hsa-mir-3129-3p
;
hsa-mir-141-5p
;
hsa-mir-3163
;
hsa-mir-548c-3p
;
hsa-mir-744-5p
Nearest miRNA
hsa-mir-10393/Upstream/6947; hsa-mir-11181/Downstream/2500802;
Nearest TSS
ENST00000557528/Upstream/11820;
ENST00000558226/Downstream/8370;
Nearest CpG islands
None/Target,
chr15-CpG: 55/Upstream/52331
,
chr15-CpG: 409/Downstream/9175
Upstream sequence
ATGCCCCTGCCAGTATTATCAGAATTAATCAGTTTCAGATCCAAACTCAGCAAAGACCTGTCGAGGGCTAGCCCAAGGGAAAGATTTGGGAAGTGGGTGA
Downstream sequence
AAGGCCGCCTCCTCCAACCTTTTGGTCATATAGCTGGCAGGGTGGTGGAGTCTAAACCTCAAGTCTTCATGGCTGACCAGGAAGGGAGAGCCCTCTCCTG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Active CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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