Basic Information
VIS ID
TVIS30002379
Fusion event
HIV-IQGAP1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
90967353/90424121 (Hg38)
End
90967353/90424121 (Hg38)
Orient
+
Location type
Intronic
Target gene
IQGAP1
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-324-3p ; hsa-mir-92a-3p ; hsa-mir-376a-3p ; hsa-mir-544a ; hsa-mir-136-3p ; hsa-mir-3074-3p ; hsa-mir-449b-3p ; hsa-mir-506-3p ; hsa-mir-506-5p
Nearest miRNA
hsa-mir-10393/Upstream/417280; hsa-mir-1302-10/Downstream/2480278;
Nearest TSS
ENST00000557528/Upstream/26240; ENST00000559682/Downstream/2031;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/35334, chr15-CpG: 166/Downstream/105336
Upstream sequence
GTAACTTTTTTTTTTTTTGGTACTGTTACGTGCTTGAGGGCCATTTTTGGCTTAGGCTGAGGTTGTTAGGTTTTCACTGTTAATGAGAACCCAAGTTAGA
Downstream sequence
TTGTCCCCTGAGAGCTGGAGTTGCCAGTAGTTGTTTGCCAGAATGATTTTATCAACATCCTTTTTAGCAGTAAAAAGATGAGATGTGTCCTTGAACTACA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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