Basic Information
VIS ID
TVIS30002389
Fusion event
HIV-MEF2A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
100150096/99609891 (Hg38)
End
100150096/99609891 (Hg38)
Orient
+
Location type
Intronic
Target gene
MEF2A
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-335-5p ; hsa-mir-155-5p ; hsa-mir-132-3p ; hsa-mir-21-5p ; hsa-mir-30a-3p ; hsa-mir-19b-3p ; hsa-mir-19a-3p
Nearest miRNA
hsa-mir-10393/Upstream/825389; hsa-mir-1302-10/Downstream/2350568;
Nearest TSS
ENST00000557528/Upstream/43408; ENST00000561125/Downstream/96704;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/43031, chr15-CpG: 84/Downstream/122805
Upstream sequence
AATTCTCCTCAAGCTTGACAAAGAGAGTATACAGTATGAGTGGGtttttatttatatattttataagaaaatatatGGCATCATTTTTGTGTGTGGAATG
Downstream sequence
TAGTTGCCTTGTCTTATATTAAAACTGGGATTAAAATTAATTGGCATTTCTTGATTCTGGTTTTTCACCATCTTTTAGCAAAGTAGACAGCCACTTGGGT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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