Basic Information
VIS ID
TVIS30002391
Fusion event
HIV-AXIN1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
366584/316584 (Hg38)
End
366584/316584 (Hg38)
Orient
+
Location type
Intronic
Target gene
AXIN1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-320c ; hsa-mir-769-3p ; hsa-mir-484 ; hsa-mir-320a ; hsa-mir-92a-3p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-6859-4/Upstream/299465; hsa-mir-11401/Downstream/218732;
Nearest TSS
ENST00000527434/Upstream/23048; ENST00000454619/Downstream/29738;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/12138, chr16-CpG: 45/Downstream/8148
Nearest cancer related gene
AXIN1(TSG, No orient, 0)
Upstream sequence
CCACAGTGTGCCCTGAGGCTGCCCCTTCCTTCTAGCGGCTGCCCCCACTcggctttgctttccctagtttcagttacttgcgttcagccaaggtctgaaa
Downstream sequence
ctaggtgcgcacagagcggtaagactgcgagagaaagagaccagctttacagggggtttatcacagtGCACCCTGACAGTCGTCAGCCTCACAGGGGGTT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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