Basic Information
VIS ID
TVIS30002519
Fusion event
HIV-CKLF integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q21
Reference genome
GRCh37/hg19
Start
66593336/66559433 (Hg38)
End
66593336/66559433 (Hg38)
Orient
+
Location type
Intronic
Target gene
CKLF
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-215-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-1225/Upstream/8787081; hsa-mir-11401/Downstream/642888;
Nearest TSS
ENST00000527434/Upstream/6038; ENST00000529718/Downstream/3695;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/6617, chr16-CpG: 39/Downstream/6688
Upstream sequence
aaaagtcctaaaagggaaaagctgggaaataggatcttcatagAACCTCTCCTCTCAAAACTACTTGATGTACACTTCAGAGCTGGACTTCGTTGGAGGG
Downstream sequence
AGGTCTAGGAGAAGAGATTACAAAGTCTTCCTCAGTTGGCCCTCATTTAGTGGCAGAAAGGGTTAAACTAAATTTTTCTAAAGATTTCTTCAAGAGGATA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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