Basic Information
VIS ID
TVIS30002557
Fusion event
HIV-WWP2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
69845471/69811568 (Hg38)
End
69845471/69811568 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA16B
Target gene
WWP2
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-23b-3p ; hsa-mir-26a-5p ; hsa-let-7a-5p ; hsa-mir-7109-5p ; hsa-mir-6885-5p ; hsa-mir-328-5p ; hsa-mir-6795-5p ; hsa-mir-6887-5p ; hsa-mir-4697-5p ; hsa-mir-4488 ; hsa-mir-1268b ; hsa-mir-1237-5p ; hsa-mir-1268a ; hsa-mir-4731-5p ; hsa-mir-6853-5p ; hsa-mir-637
Nearest miRNA
hsa-mir-1225/Upstream/245700; hsa-mir-11401/Downstream/121513;
Nearest TSS
ENST00000527434/Upstream/12522; ENST00000563618/Downstream/27169;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/48902, chr16-CpG: 77/Downstream/153566
Upstream sequence
aTAgcagggtctggtggcttatacctccccacactttgggaggctgaggtgggaggccctcttgagcctaggagtttgagaccagactcagtattgtagt
Downstream sequence
gagacacagtctctacaaaaataaaaataaaggaaatagctgggcatggtgggcatgcaacggtagtcccagccacttgggaggctgaggtgggaggatc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate