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VISDB
Viral Integration Site DataBase
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TVIS30002599
Basic Information
VIS ID
TVIS30002599
Fusion event
HIV-METTL16 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
2357882/2454588 (Hg38)
End
2357882/2454588 (Hg38)
Orient
+
Location type
Intronic
Target gene
METTL16
miRNAs that regulate target gene
hsa-mir-26b-5p
;
hsa-mir-193b-3p
;
hsa-mir-423-3p
;
hsa-mir-92a-3p
;
hsa-mir-1178-3p
;
hsa-mir-3941
;
hsa-mir-4643
;
hsa-mir-603
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-8485
;
hsa-mir-587
;
hsa-mir-3692-3p
;
hsa-mir-3156-3p
;
hsa-mir-1260b
;
hsa-mir-1260a
;
hsa-mir-188-3p
;
hsa-mir-6509-3p
;
hsa-mir-4436b-5p
;
hsa-mir-3119
;
hsa-mir-876-5p
;
hsa-mir-3167
;
hsa-mir-627-3p
;
hsa-mir-6777-3p
Nearest miRNA
hsa-mir-132/Upstream/404208; hsa-mir-10226/Downstream/238273;
Nearest TSS
ENST00000595228/Upstream/34819;
ENST00000571289/Downstream/23297;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/52398
,
chr17-CpG: 26/Downstream/57179
Upstream sequence
CTTTTATCCTATGCTCTTATAAGTGATTTTAATTATTCACTTTTTGACATGGATAAGACTATATTATTATTATTAtttttttttttttttttttgagacg
Downstream sequence
gagtcttgctcagccgcccagggtggagtgcagtggcatgatctcagctcactgcaaccactgtctcctgggttcaagcaattttcccatctcagcctcc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Active CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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