Basic Information
VIS ID
TVIS30002620
Fusion event
HIV-DERL2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
5381015/5477695 (Hg38)
End
5381015/5477695 (Hg38)
Orient
+
Location type
Intronic
Target gene
DERL2
miRNAs that regulate target gene
hsa-mir-324-3p ; hsa-mir-1468-5p ; hsa-mir-4694-3p ; hsa-mir-374c-5p ; hsa-mir-655-3p ; hsa-mir-4769-3p ; hsa-mir-335-3p ; hsa-mir-1231 ; hsa-mir-632 ; hsa-mir-4288 ; hsa-mir-6749-3p ; hsa-mir-6755-3p ; hsa-mir-4469 ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-5196-3p ; hsa-mir-548b-3p ; hsa-mir-6516-3p ; hsa-mir-6077 ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125 ; hsa-mir-5680 ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-3121-3p ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-548v ; hsa-mir-187-5p ; hsa-mir-500a-3p ; hsa-mir-8059 ; hsa-mir-4471 ; hsa-mir-1292-5p ; hsa-mir-4252 ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-4793-5p
Nearest miRNA
hsa-mir-1253/Upstream/507545; hsa-mir-10226/Downstream/1177745;
Nearest TSS
ENST00000595228/Upstream/8603; ENST00000574186/Downstream/2578;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/8697, chr17-CpG: 84/Downstream/8375
Upstream sequence
ggtgtgcaataagaatagggaactattaattacagaatctatgtggtggctacatgaagctcactccaatttttttctgatttcctataagtttgttaat
Downstream sequence
tttcataataaaatattggaggaaaCCAATaggaaaaaagctagaatgaaccatgaggtagtactagaaatgggagtatagtataaacccatgttttaaa
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate