Basic Information
VIS ID
TVIS30002700
Fusion event
HIV-MED24 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
38205501/40049248 (Hg38)
End
38205501/40049248 (Hg38)
Orient
+
Location type
Intronic
Target gene
MED24
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-98-5p ; hsa-mir-24-3p ; hsa-mir-766-3p ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-320a ; hsa-mir-197-3p ; hsa-mir-16-5p ; hsa-mir-3680-3p ; hsa-mir-3941 ; hsa-mir-216b-3p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-8067 ; hsa-mir-6508-5p
Nearest miRNA
hsa-mir-1180/Upstream/22839; hsa-mir-10226/Downstream/112685;
Nearest TSS
ENST00000595228/Upstream/15573; ENST00000577288/Downstream/4064;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/68011, chr17-CpG: 19/Downstream/5266
Upstream sequence
tgggcaacatagtgagaccccgtttccacaaaaaatacaaaaaAAGAAAAAGGAGAAAAAAGAAAAGAAAAAGGGGTCCTGAGAGCAAACTCcttttctc
Downstream sequence
tagccataccaaattattttcagttcctgaacaacattatgtgatttttgcctcccaccgtgtacatatgcttttctctgctttgcacacacactctcct
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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