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Viral Integration Site DataBase
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TVIS30002720
Basic Information
VIS ID
TVIS30002720
Fusion event
HIV-STAT3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
40535085/42383067 (Hg38)
End
40535085/42383067 (Hg38)
Orient
+
Location type
Intronic
Target gene
STAT3
miRNAs that regulate target gene
hsa-mir-20b-5p
;
hsa-mir-125b-5p
;
hsa-mir-337-3p
;
hsa-mir-155-5p
;
hsa-mir-93-5p
;
hsa-mir-21-5p
;
hsa-mir-92a-3p
;
hsa-mir-20a-5p
;
hsa-let-7e-5p
;
hsa-mir-124-3p
;
hsa-mir-130b-3p
;
hsa-mir-106a-5p
;
hsa-mir-106b-5p
;
hsa-mir-874-3p
;
hsa-mir-4516
;
hsa-mir-17-5p
;
hsa-mir-200a-3p
;
hsa-mir-544a
;
hsa-mir-181a-5p
;
hsa-mir-1234-3p
;
hsa-mir-1181
;
hsa-mir-6878-5p
;
hsa-mir-5681a
;
hsa-mir-6837-5p
;
hsa-mir-4685-5p
;
hsa-mir-7113-5p
;
hsa-mir-6754-5p
;
hsa-mir-4270
;
hsa-mir-4441
;
hsa-mir-922
;
hsa-mir-6760-5p
;
hsa-mir-1288-5p
;
hsa-mir-6871-3p
;
hsa-mir-6809-3p
;
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-1178-3p
;
hsa-mir-7158-5p
;
hsa-mir-4684-5p
;
hsa-mir-138-2-3p
;
hsa-mir-371b-3p
;
hsa-mir-548n
;
hsa-mir-6875-3p
;
hsa-mir-5581-3p
;
hsa-mir-4778-3p
;
hsa-mir-7110-3p
;
hsa-mir-6845-3p
;
hsa-mir-877-3p
;
hsa-mir-618
;
hsa-mir-6807-5p
;
hsa-mir-4720-3p
;
hsa-mir-6762-3p
;
hsa-mir-4804-3p
;
hsa-mir-6872-3p
;
hsa-mir-7151-3p
;
hsa-mir-5095
;
hsa-mir-365b-5p
;
hsa-mir-365a-5p
;
hsa-mir-8052
;
hsa-mir-3199
;
hsa-mir-6789-3p
;
hsa-mir-500b-3p
;
hsa-mir-4438
;
hsa-mir-519d-3p
;
hsa-mir-520c-3p
;
hsa-mir-125a-5p
;
hsa-mir-21-3p
;
hsa-mir-519a-3p
;
hsa-mir-148a-3p
;
hsa-mir-223-3p
;
hsa-let-7c-5p
;
hsa-mir-29b-1-5p
;
hsa-mir-23a-3p
;
hsa-mir-323a-3p
;
hsa-mir-375
;
hsa-mir-124-5p
;
hsa-mir-29b-3p
;
hsa-let-7a-5p
;
hsa-mir-340-5p
;
hsa-mir-410-5p
Nearest miRNA
hsa-mir-1180/Upstream/865850; hsa-mir-10226/Downstream/111706;
Nearest TSS
ENST00000595228/Upstream/34551;
ENST00000589213/Downstream/5347;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/70138
,
chr17-CpG: 87/Downstream/4752
Nearest cancer related gene
STAT3
(OG, No orient, 0)
Upstream sequence
ATGACAAATGAGAACTGACCATAACAGAAATTCATTCTTCCATATGTTATTCCCAGGCCTCATAACCTCTCCTTCCTCTGAAGACATGTAGCATTCAGTG
Downstream sequence
TAGCACTGTCAGAATgtctcactctgtcccccagtctggagtgcagtggcaggatcttggctcactgcagcctccacctcccaggttcaagcaattctcc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Active CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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