Basic Information
VIS ID
TVIS30002746
Fusion event
HIV-KPNB1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
45745643/47668277 (Hg38)
End
45745643/47668277 (Hg38)
Orient
-
Location type
Exonic
Target gene
KPNB1
miRNAs that regulate target gene
hsa-mir-1296-5p ; hsa-mir-1236-3p ; hsa-mir-1229-3p ; hsa-mir-877-3p ; hsa-mir-744-5p ; hsa-mir-455-3p ; hsa-mir-766-3p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-320a ; hsa-mir-149-5p ; hsa-mir-128-3p ; hsa-mir-125b-5p ; hsa-mir-222-3p ; hsa-mir-181b-5p ; hsa-mir-7-5p ; hsa-mir-92a-3p ; hsa-mir-30d-5p ; hsa-mir-566 ; hsa-mir-4496 ; hsa-mir-525-3p ; hsa-mir-524-3p ; hsa-mir-4484 ; hsa-mir-9-5p ; hsa-mir-2681-5p ; hsa-mir-581 ; hsa-mir-4455
Nearest miRNA
hsa-mir-1180/Upstream/695177; hsa-mir-10226/Downstream/364605;
Nearest TSS
ENST00000595228/Upstream/11352; ENST00000583013/Downstream/88;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/17421, chr17-CpG: 147/Downstream/25464
Upstream sequence
TTCACCAGGACGAAAATGATGATGACGATGACTGGAACCCCTGCAAAGCAGCAGGGGTGTGCCTCATGCTTCTGGCCACCTGCTGTGAAGATGACATTGT
Downstream sequence
CCCACATGTCCTCCCCTTCATTAAAGAACACATCAAGAACCCAGATTGGCGGTACCGGGATGCAGCAGTGATGGCTTTTGGTTGTATCTTGGAAGGACCA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate