Basic Information
VIS ID
TVIS30002826
Fusion event
HIV-SEPTIN9 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
75410147/77414065 (Hg38)
End
75410147/77414065 (Hg38)
Orient
-
Location type
Intronic
Target gene
SEPTIN9
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-186-5p ; hsa-mir-10a-5p ; hsa-mir-5587-5p ; hsa-mir-670-5p ; hsa-mir-6791-5p ; hsa-mir-4292 ; hsa-mir-4308 ; hsa-mir-216b-3p ; hsa-mir-4802-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-6500-3p ; hsa-mir-4717-3p ; hsa-mir-3614-5p ; hsa-mir-128-1-5p ; hsa-mir-128-2-5p ; hsa-mir-1914-3p ; hsa-mir-3144-5p ; hsa-mir-3184-5p ; hsa-mir-3191-3p ; hsa-mir-3677-3p ; hsa-mir-423-5p ; hsa-mir-4652-5p ; hsa-mir-4655-3p ; hsa-mir-4710 ; hsa-mir-491-5p ; hsa-mir-5194 ; hsa-mir-6734-5p ; hsa-mir-6738-5p ; hsa-mir-6781-5p ; hsa-mir-6795-3p ; hsa-mir-6804-5p ; hsa-mir-6810-5p ; hsa-mir-6826-3p ; hsa-mir-6882-3p ; hsa-mir-6887-3p
Nearest miRNA
hsa-mir-10226/Upstream/17011; hsa-mir-1250/Downstream/2293111;
Nearest TSS
ENST00000595228/Upstream/8988; ENST00000590917/Downstream/5737;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/11620, chr17-CpG: 35/Downstream/37330
Nearest cancer related gene
SEPTIN9(OG, No orient, 0)
Upstream sequence
tctttttttctttttgtttgtttgttttGGAGAGAGGGAAGGCTTTTTTTCATTTTtttttaaacagctttattgagatccaagtaagctactatacaat
Downstream sequence
ccaccaatttatttatttatttatttttttgagacggagtttcactcttgtcgcctaggctggagtgcagtggcgccatctcggctgactgcaacctccg
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate