Basic Information
VIS ID
TVIS30002897
Fusion event
HIV-ME2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
48411471/50885101 (Hg38)
End
48411471/50885101 (Hg38)
Orient
+
Location type
Intronic
Target gene
ME2
miRNAs that regulate target gene
hsa-mir-92a-3p ; hsa-mir-1228-3p ; hsa-mir-1273g-3p ; hsa-mir-194-5p ; hsa-mir-4490 ; hsa-mir-4793-3p ; hsa-mir-508-5p ; hsa-mir-6512-3p ; hsa-mir-6720-5p ; hsa-mir-766-3p ; hsa-mir-7703
Nearest miRNA
hsa-mir-1-2/Upstream/758538; hsa-mir-122/Downstream/2352000;
Nearest TSS
ENST00000575820/Upstream/5873; ENST00000638768/Downstream/10724;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/5488, chr18-CpG: 62/Downstream/82805
Upstream sequence
cggtcaccacacccagctaattttttgtgtttttagtagagacagggttttgccatgttggccagtctgatcccgaactcctggtctcaggtgatctgcc
Downstream sequence
tgcctcagcctcccaaagtgctgggatttcaggcatgagccaccacgccaggccCAAAGTTTTAACTGTAGTAAATAATGCTATCTCTCCTGGAAGAGCC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate