Basic Information
VIS ID
TVIS30002898
Fusion event
HIV-POLI integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
51808158/54281788 (Hg38)
End
51808158/54281788 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA18B
Target gene
POLI
miRNAs that regulate target gene
hsa-mir-92a-3p ; hsa-mir-27b-5p ; hsa-mir-4255 ; hsa-mir-3591-5p ; hsa-mir-5197-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-4760-5p ; hsa-mir-548aw ; hsa-mir-8061 ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-340-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-4786-5p ; hsa-mir-769-5p ; hsa-mir-889-3p ; hsa-mir-1277-5p ; hsa-mir-142-3p ; hsa-mir-376a-5p ; hsa-mir-455-5p ; hsa-mir-203a-3p ; hsa-mir-3190-5p ; hsa-mir-3926 ; hsa-mir-513b-3p ; hsa-mir-548s ; hsa-mir-5583-3p ; hsa-mir-6849-3p
Nearest miRNA
hsa-mir-1-2/Upstream/1044598; hsa-mir-122/Downstream/1197433;
Nearest TSS
ENST00000575820/Upstream/6891; ENST00000583576/Downstream/1066;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/11826, chr18-CpG: 82/Downstream/75789
Upstream sequence
aggactatatactggtgcaaaacattcttacttggctttactttcgagttcttgtatcttttttttttttttttaacaggctttctcctttctcacttat
Downstream sequence
tgccaaattgccaaccttcttttttttctgctgtgaaaaatctgtcactctactttaatagttccccctacatagccatctcctccaacttactgctttt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate