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TVIS30002905
Basic Information
VIS ID
TVIS30002905
Fusion event
HIV-BCL2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
60898616/63231383 (Hg38)
End
60898616/63231383 (Hg38)
Orient
+
Location type
Intronic
Target gene
BCL2
miRNAs that regulate target gene
hsa-mir-34b-5p
;
hsa-mir-21-5p
;
hsa-mir-204-5p
;
hsa-mir-153-3p
;
hsa-let-7a-5p
;
hsa-mir-15a-5p
;
hsa-mir-15b-5p
;
hsa-mir-16-5p
;
hsa-mir-34a-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-29c-3p
;
hsa-mir-29b-3p
;
hsa-mir-29a-3p
;
hsa-mir-34b-3p
;
hsa-mir-181d-5p
;
hsa-mir-181c-5p
;
hsa-mir-181b-5p
;
hsa-mir-181a-5p
;
hsa-mir-34c-5p
;
hsa-mir-33b-5p
;
hsa-mir-192-5p
;
hsa-mir-195-5p
;
hsa-mir-630
;
hsa-mir-451a
;
hsa-mir-365a-3p
;
hsa-mir-125b-5p
;
hsa-mir-449a
;
hsa-mir-200b-3p
;
hsa-mir-200c-3p
;
hsa-mir-429
;
hsa-mir-136-5p
;
hsa-mir-7-5p
;
hsa-mir-148a-3p
;
hsa-mir-24-2-5p
;
hsa-mir-182-5p
;
hsa-mir-196b-5p
;
hsa-mir-143-3p
;
hsa-mir-375
;
hsa-mir-215-5p
;
hsa-mir-103a-3p
;
hsa-mir-96-5p
;
hsa-mir-205-5p
;
hsa-mir-126-3p
;
hsa-mir-18a-5p
;
hsa-mir-497-5p
;
hsa-mir-1915-3p
;
hsa-mir-206
;
hsa-mir-34a-3p
;
hsa-mir-448
;
hsa-mir-125a-5p
;
hsa-mir-708-5p
;
hsa-mir-184
;
hsa-mir-30b-5p
;
hsa-mir-135a-5p
;
hsa-mir-224-5p
;
hsa-mir-503-5p
;
hsa-mir-494-3p
;
hsa-mir-211-5p
;
hsa-mir-9-5p
;
hsa-mir-139-5p
;
hsa-mir-26a-1-3p
;
hsa-mir-1284
;
hsa-mir-376c-3p
;
hsa-mir-190b
;
hsa-mir-15a-3p
;
hsa-mir-16-1-3p
;
hsa-mir-98-5p
Nearest miRNA
hsa-mir-1-2/Upstream/4780225; hsa-mir-5011/Downstream/3850201;
Nearest TSS
ENST00000575820/Upstream/23761;
ENST00000589905/Downstream/87429;
Nearest CpG islands
None/Target,
chr18-CpG: 67/Upstream/514245
,
chr18-CpG: 236/Downstream/86887
Nearest cancer related gene
BCL2
(OG, No orient, 0)
Upstream sequence
taaaatcagcaactagataaatatgtcttctctctcaccactctattcattattgtatgagataccttgctgatgtaataaagcaagaaaaaggagtaag
Downstream sequence
aaaatcagaattagaaatgaagggggaatatgtggcattatttgcaaatgataagattgtctacatagataatccatgagaaactatgaacaattacaag
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Active CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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