Basic Information
VIS ID
TVIS30002908
Fusion event
HIV-DIPK1C integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
72122116/74454881 (Hg38)
End
72122116/74454881 (Hg38)
Orient
+
Location type
Intronic
Target gene
DIPK1C
miRNAs that regulate target gene
hsa-mir-449c-3p ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-548aw ; hsa-mir-6868-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-4666a-3p ; hsa-mir-7849-3p ; hsa-mir-574-5p ; hsa-mir-6867-5p ; hsa-mir-3650 ; hsa-mir-4455 ; hsa-mir-6124 ; hsa-mir-3148 ; hsa-mir-3688-3p ; hsa-mir-892a
Nearest miRNA
hsa-mir-1-2/Upstream/1601499;
Nearest TSS
ENST00000575820/Upstream/45433; ENST00000580229/Downstream/2387;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/138372, chr18-CpG: 138/Downstream/1490
Upstream sequence
CCCTGTCCTGAGAGTGTCCTGGGTAAAATTTGAGCCAGGGCACTGTGTGGATCTCGCATCAACACATCCAGGATGAAAACGGTAGAAAAGGAAGTGGCAG
Downstream sequence
GAAGACAGGGGGAGAAAGAGTTCTGAGAATGTGTAAAGAGTAAGGAACTCAAACAGGGCCTGTGGCAAAGTCTGCTCCCCCACAAACCAGTTCGTGGAGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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