Basic Information
VIS ID
TVIS30002972
Fusion event
HIV-SPC24 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
11258889/11148213 (Hg38)
End
11258889/11148213 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
SPC24
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-92b-3p ; hsa-mir-6888-3p ; hsa-mir-3120-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-6834-3p ; hsa-mir-3664-5p ; hsa-mir-3156-5p ; hsa-mir-665 ; hsa-mir-4443 ; hsa-mir-6515-5p ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-5690 ; hsa-mir-4684-5p ; hsa-mir-4738-3p ; hsa-mir-3675-3p ; hsa-mir-1273a ; hsa-mir-340-3p ; hsa-mir-3613-3p ; hsa-mir-3672 ; hsa-mir-4486 ; hsa-mir-4649-5p ; hsa-mir-4797-5p ; hsa-mir-5586-3p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6729-5p ; hsa-mir-6827-3p ; hsa-mir-6849-3p ; hsa-mir-6864-3p ; hsa-mir-759 ; hsa-mir-873-3p ; hsa-mir-939-3p
Nearest miRNA
hsa-mir-1181/Upstream/34679; hsa-let-7e/Downstream/347331;
Nearest TSS
ENST00000633603/Upstream/20666; ENST00000588634/Downstream/7548;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/42582, chr19-CpG: 44/Downstream/7341
Upstream sequence
CTGAGTAGGGCAGGTCGTTAAGGACCCCGGCTTTCGAGAGAGGGCTGCCCCTGCGCTAACTGCAGCTGGGAGGCCCAGGGTCTTGGCTCTATTTACGCAC
Downstream sequence
ACtctcttctttgagtcagagttttgctttgtcacccaggctggagtgcagtggcacgacctcagctcactgcaacctctgcctcccaggctgaagtgat
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate